Runes are made from carved chunks of whalebone. They are resources which are found throughout the city of game world. They can more easily located using the Heart which was given to Corvo by the Outsider at the beginning of Dishonored. They are used to acquire supernatural powers which help Corvo complete his missions.
In Dishonored 2[]
The first rune available in Dishonored 2 is found in the Void after Emily's first encounter with the Outsider.
A Strange Visit[]
- 1 rune inside the Void on the Outsider shrine
- 1 rune inside the sunken boat beside the Dreadful Wale
Edge of the World / Dockyard Quarter[]
8 [1] runes total:
- 1 rune Black Market shop, 400 or looted
- 1 rune on the platform by the Karnaca Enclave where the Overseer is preaching
- 1 rune in the sewer, beyond the grate at the west end of the canal (tricky to get)
- 1 rune inside the mouth of the whale carcass on the docks
- 1 rune inside the safe in the Vice Overseer's office on the third floor of the Karnaca Enclave
- 2 runes on the Outsider shrine in the apartment across from the Enclave
The Good Doctor / Addermire Institute[]
6 runes total:
- 1 rune mounted on a plaque on a pillar next to a small table in the guard area by the Dining Hall
- 1 rune in the Recuperation area in the Bloodfly nests nearest the elevator shaft
- 1 rune in the Lost and Found, with Vera Moray's Belongings
- 1 rune in the small room above Hamilton's Quarters (reachable by exiting hamilton's quarters and using Far Reach / Blink to get to the open shutter above the door)
- 2 runes on the Outsider shrine in the second last private room on the fourth floor, west wing
The Clockwork Mansion / Aventa District[]
6 runes total:
- 2 runes on the Outsider shrine on the third floor of the quarantined building in the west block of apartments in Lower Aventa District
- 1 rune in a dresser in the pile of rubbish in the center of the Pawn Shop Area behind Aventa Station
- 1 rune can be purchased or looted from the Black Market Shop
- 1 rune is in the back room of the apartment with the maid off the Side Alley in [[Upper Aventa District
- 1 rune on one of the platforms in the Laboratory, along with a Letter from Delilah
The Royal Conservatory / Cyria Gardens[]
6 runes total:
- 1 rune can be purchased at the Black Market Shop
- 2 runes on the Outsider shrine on the top floor of the booby-trapped building behind Winnow's Bar
- 1 rune inside a small glass case in the Archive in the basement of Conservatory
- 1 rune in the seating area at the southwest end of the second floor of the Conservatory
- 1 rune by the couch with all the grapes on the roof
Dust District[]
5 runes total:
- 1 rune in the derelict apartment below Meagan's hideout
- 2 runes on the Outsider shrine in Paolo's Apartment
- 1 rune inside a chest in the Confiscation room of the Overseer Outpost
- 1 rune in the quarantined (bloodfly-infested) building on the second floor
A Crack in the Slab / Aramis Stilton's Manor[]
4 runes total:
- 1 rune inside the flooded room off the basement, in the present (1852) timeline, after fixing the valve
- 1 rune in the photography studio, in a crate by the window, in the past (1849) timeline
- 1 rune on the second floor above the entrance, near an empty safe, in the present timeline
- 1 rune in the scaffolding outside the Stilton Manor in the altered present timeline.
The Grand Palace / Palace District[]
5 runes total:
- 1 rune in the cupboard under the sink in the Nest Keeper's apartment on the north side of Ravina Boulevard
- 2 runes on the Outsider shrine in the underground chamber behind the Black Market Shop
- 1 rune inside the safe in the First Captain's Office
- 1 rune in the flooded section of the Abandoned Storage area
Death to the Empress / Tower District[]
5 runes total:
- 1 rune can be purchased from the Black Market Shop at the former Black Pony Pub
- 2 runes on the Outsider shrine in a secret room on the top floor of the apartment 3 buildings past the Dunwall Courier offices
- 1 rune inside the Security Room, on top of the pipes in the ceiling by the whale oil tanks
- 1 rune in a crawlspace under the stairs in the pump room
In Dishonored[]
Hound Pits Pub visit #1[]
3 total:
- 1 after the first mission, received from the Outsider
- 1 near the sewer grate by the dock near the Hound Pits Pub
- 1 rune can be purchased from Piero for 500
High Overseer Campbell[]
7 total:
- 2 runes are obtained from Granny Rags: one for helping her with her "Gentlemen callers" and a second for poisoning the elixirs made by the Bottle Street Gang
- 1 rune is found at the Outsider shrine behind Granny Rags' Apartment
- 1 rune in the guard post on John Clavering Boulevard near the end of Gaff Street, along with a note
- 1 rune mounted above the fireplace in the Meeting Chamber of the Office of the High Overseer
- 1 rune in Campbell's Secret Chamber
- 1 rune in the Workshop in the Back Yard of the Office of the High Overseer
Hound Pits Pub visit #2[]
2 total:
- 2 in the sewers under the Hound Pits Pub
House of Pleasure[]
5 total:
- 1 rune in the secret room behind the bookcase on the second floor of Dr. Galvani's Offices
- 1 rune in the safe in the Art Dealer's Apartment
- 1 rune on the second floor inside the building on the east side of the main gate to The Golden Cat
- 1 rune in the first bedroom as you enter the dormitory on the third floor of The Golden Cat
- 1 rune mounted on the wall on the second floor of The Golden Cat
The Royal Physician[]
5 total:
- 1 rune in the safe on the third floor of Pratchett's House
- 1 rune on the top floor of Sokolov's House
Lady Boyle's Last Party[]
3 total:
- 1 rune on the Outsider shrine on the second floor apartment on the same side of the canal as the guard tower in the Estate District
- 1 rune underwater at the west end of the canal
- 1 rune in the Basement Vault of the Boyle Estate, inside the chest
Hound Pits Pub visit #5[]
- 1 rune for dueling Lord Shaw, received from Lord Pendleton
- 1 rune for not killing all the Boyle sisters, recieved as an anonymous gift from a surviving sister
- 1 rune from Emily if Corvo finds her for Callista
Return to the Tower[]
4 total:
- 1 rune in sleeping quarters near the pumphouse
- 1 rune in the Lord Regent's Safe Room in Dunwall Tower
- 1 rune inside the Lord Regent's Chambers in Dunwall Tower
- 1 rune on the Outsider shrine in the torturer's chambers in the basement of Dunwall Tower
The Flooded District[]
- 5 total
The Loyalists[]
- 1 rune on the second floor of Piero's Workshop
The Light at the End[]
- 1 during The Light at the End mission
Notes[]
- ↑ 2 of the 10 runes listed in the end of mission stats screen are actually from "A Strange Visit"